Short Wave What Do Stem Cells Mean For The Future Of Parkinson's?
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Sep 16, 2025 Dr. Claire Henchcliffe is a leading neurologist at UC Irvine, dedicated to advancing Parkinson’s research. She discusses the rise in Parkinson’s cases and highlights breakthroughs in treatment options, particularly the use of stem cells. Listeners will find her insights on early symptoms and neurological changes captivating. The potential of stem cell transplants is explored, emphasizing patient progress and the hope for future therapies that may even prevent the disease altogether. Join the conversation about the evolving landscape of brain science!
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Parkinson's Rising Public-Health Concern
- Parkinson's is a growing neurodegenerative disease affecting about a million Americans and rising with aging populations.
- Claire Henchcliffe highlights Parkinson's as the fastest-growing common neurodegenerative disorder after Alzheimer's.
Alpha-Synuclein And Dopamine Loss
- Misfolded alpha-synuclein proteins form clumps linked to neuron damage and loss in Parkinson's.
- This particularly harms dopamine-producing cells in the substantia nigra, reducing dopamine critical for coordination.
Replace Dopamine With Levodopa
- Use carbidopa-levodopa to replace brain dopamine and improve motor symptoms in Parkinson's.
- This medication has been the gold standard since the 1950s and 1960s.