

Methylene Blue: Panacea or Poison? The Truth You Haven’t Heard
Apr 11, 2025
Is methylene blue a miracle or a mistake? The discussion dives into its fascinating history and controversial uses in medicine, especially for conditions like methemoglobinemia and septic shock. Compelling insights reveal both its potential benefits and serious risks, urging caution for daily users. The host critically evaluates available evidence and highlights the importance of considering safer alternatives, like vitamin C. This thorough breakdown equips listeners with essential information amid the hype surrounding this trending substance.
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Methylene Blue's Origins
- Methylene blue was first invented in 1876 from the coal tar chemical dye industry.
- It became the first fully synthetic medicine, evolving from dyes that also led to antibiotics.
Methemoglobinemia Treatment Paradox
- Methylene blue treats methemoglobinemia by restoring iron in hemoglobin to its proper state.
- However, it relies on NADPH; high doses can paradoxically cause the condition it aims to cure.
Methylene Blue in Septic Shock
- Methylene blue can raise blood pressure in septic shock patients and reduce the need for other drugs.
- Yet, it causes lung toxicity and no proven improvement in survival or overall outcome.