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When evaluating the top ERP systems for the pharmaceutical industry, it’s crucial to recognize that this list focuses solely on the ERP solutions themselves—not the vendors behind them—and spans organizations of all sizes, from emerging biotech startups to large-scale pharmaceutical manufacturers. Since ERP needs vary widely across the pharma value chain, the accompanying commentary offers essential guidance on which systems best serve specific market segments. The industry encompasses a wide array of business models, including traditional pharma companies, biotech firms, cannabis producers, nutraceutical manufacturers, CROs, and R&D consultancies—each with distinct regulatory, operational, and supply chain demands. For instance, a contract research organization may require robust data integrity and clinical compliance tools, whereas a nutraceutical producer might prioritize batch traceability and rapid production scalability. These differences underscore the importance of selecting an ERP system that not only supports compliance but also aligns with a company’s core processes and growth trajectory.

In this episode, our host Sam Gupta discusses the top 10 pharma ERP systems in 2025. He also discusses several variables that influence the rankings of these pharma ERP systems. Finally, he shares the pros and cons of each pharma ERP system.

Background Soundtrack: Away From You – Mauro Somm

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