

S7 Ep153: Say Cheese! Eye Spy Retinoblastoma
Sep 24, 2025
Dr. Basil Williams, a combined ocular oncologist and vitreoretinal disease specialist at Bascom Palmer Eye Institute, shares invaluable insights on Retinoblastoma. He discusses the role of smartphones in early detection through white reflex, emphasizing that leukocoria should always be treated as Retinoblastoma until proven otherwise. The conversation also highlights recent advancements in genetic testing and AI diagnostics, as well as the importance of regular screening. Dr. Williams stresses the need for urgent intervention and effective communication with families to ensure better outcomes.
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Refer Immediately For Leukocoria
- If you see a white (abnormal) red reflex, refer urgently to pediatric ophthalmology.
- Treat leukocoria as retinoblastoma until proven otherwise to avoid delay.
Rapid Growth And High Survival
- Retinoblastoma is the most common intraocular cancer in children and worldwide.
- It doubles rapidly (about every two weeks) so early detection preserves life and vision.
Make Red Reflex Checks Routine
- Routinely check the red reflex at well-child visits and ask parents about photos if exam is challenging.
- If any suspicion exists, obtain an expedited ophthalmology evaluation rather than waiting.