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The Drug Discovery World Podcast
DDW Highlights: 29 January 2024
Jan 29, 2024
The podcast highlights the most studied disease area in 2023, advancements in the treatment of colorectal, pancreatic, lung cancer, and leukaemia. It also discusses challenges in clinical development, predictive analytics, digital patient profiles, positive phase one B study on treating metastatic colorectal cancer, enhanced response rates in cancer trials, investigational drug combinations for pancreatic cancer, microbiome-based immunotherapy in cancer treatment, and FDA orphan drug designation for AML treatment.
14:20
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Quick takeaways
- Breast cancer remains the most studied disease in 2023, with promising advancements in colorectal, pancreatic, and lung cancer treatments.
- The increase in phase two clinical trial attrition rates poses challenges for new therapy development and clinical development cost control.
Deep dives
Breast Cancer Most Studied Disease in 2023
Breast cancer remained the most studied disease in 2023 for the third consecutive year, followed by solid tumors, stroke, COVID-19, and prostate cancer. Fezi's analysis of 65,749 clinical trials showed that the US holds 33% of investigator sites globally, indicating a strong presence in interventional trials. The increase in trial recruitment across the top five indications, particularly in solid tumor trials, suggests promising developments in innovative cancer therapies.
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