Two guys talking **it - A Gastroenterology and Hepatology podcast #10: A/Prof Gianluca Ianiro and Dr Benjamin Mullish - The gut microbiome in health and disease
Today we’re talking bugs, bowels, and breakthroughs with A/Prof Gianluca Ianiro and Dr. Ben Mullish, two microbiome maestros who make poo science strangely fascinating.
A/Prof Gianluca Ianiro is an Associate Professor of Gastroenterology at the Università Cattolica del Sacro Cuore in Rome and a Consultant at the Gastroenterology Unit of the Fondazione Policlinico Universitario Agostino Gemelli IRCCS. His clinical and research interests center on the gut microbiota, with a particular emphasis on fecal microbiota transplantation (FMT) and its applications in gastrointestinal disorders such as Clostridioides difficile infection and irritable bowel syndrome. Recognized as a leading expert in his field, Professor Ianiro has contributed extensively to international consensus guidelines and has been acknowledged for his work with the United European Gastroenterology Rising Star award. He also leads the Microbiome Clinic at Gemelli, translating cutting-edge microbiome research into clinical practice.
Dr. Benjamin Mullish is a Senior Clinical Research Fellow in the Division of Digestive Diseases at Imperial College London and an Honorary Consultant in Hepatology and Gastroenterology at St Mary’s Hospital, part of the Imperial College Healthcare NHS Trust. He is also an IPPRF Research Fellow within the Department of Metabolism, Digestion and Reproduction at Imperial College. His research focuses on the gut microbiome and faecal microbiota transplantation (FMT), particularly in the context of liver disease and gastrointestinal infections.This conversation delves into the complexities of the microbiome, particularly the gut microbiome, and its significant role in health and disease.
We discuss the dynamic nature of the microbiome, the challenges in microbiome research, and the potential for microbiome-based therapeutics. They also explore the roles of prebiotics and probiotics, the future of microbiome diagnostics, and the potential future concept for specialised microbiome clinicians to bridge the gap between research and clinical practice.
As always comments, questions and feedback please send to: X: @2guystalkingit
Email: 2guystalkingit@gmail.com
Chapters
00:20 J + J Introduction
05:11 Introduction to the Microbiome
07:16 Understanding the Gut Microbiome
10:04 The Dynamic Nature of the Microbiome
13:21 Factors Influencing the Gut Microbiome
16:15 Clinical Relevance of Stool Microbiome
19:24 Microbiome and Disease: Cancer and Liver Health
22:12 Microbiome in Inflammatory Bowel Disease (IBD) and Metabolism
25:20 Future Directions in Microbiome Research
35:20 The Uncertainty of Microbial Therapeutics
37:10 The Future of Microbiome Research
42:41 Understanding Prebiotics and Probiotics
56:49 The Need for Microbiome Clinician specialists