
 Theoretical Neuroscience Podcast
 Theoretical Neuroscience Podcast On computational neurotechnology for the clinic - with Anthony Burkitt, Nada Yousif & Esra Neufeld - #33
 Oct 11, 2025 
 In this engaging discussion, computational neuroscientists Anthony Burkitt, Nada Yousif, and Esra Neufeld explore the cutting-edge intersection of neurotechnology and clinical applications. They dive into the evolution of cochlear implants and the intricacies of subretinal visual prostheses. With insights on deep brain stimulation, Esra reveals how personalized modeling has accelerated spinal stimulation tuning. The trio also discusses the future of ultrasound neuromodulation and the importance of transparent models in regulatory safety. An enlightening dialogue on transforming patient care! 
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From Bionic Ear To Closed‑Loop Vision
- Anthony Burkitt described working with Graham Clark on cochlear implants and later retinal prostheses.
- He emphasized moving from open-loop stimulation to closed-loop models that measure and titrate neural responses.
Two‑Part Modeling For DBS
- Nada Yousif split modeling into electric field spread and neuronal activation to guide DBS.
- She highlighted finite element models feeding extracellular potentials into axon models to predict stimulation effects.
Modeling Made Spinal Cord Therapy Practical
- Esra Neufeld recounted modeling spinal cord stimulation and why rodent successes failed in humans.
- Personalized models reduced tuning time from months to a single day and restored walking motions with therapy.
