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Thorough Bleeding History
- Ask about all bleeding types, including nosebleeds, mouth bleeds, bruising, and menses.
- Inquire about methods used to stop bleeding and provide tips if needed.
Varied VWD Presentation
- Von Willebrand disease (VWD) has varied presentations, with some patients having isolated symptoms while others experience widespread bleeding.
- There's no single classic presentation, and symptoms can range from mild to severe, even with identical VWF levels.
VWF's Dual Role
- Von Willebrand Factor (VWF) is crucial for primary hemostasis (platelet plug formation).
- It's also vital in secondary hemostasis, protecting factor VIII from degradation.