REPLAY: Mast Cell Activation Syndrome with Dr Michelle Woolhouse & Beth O'Hara
Apr 1, 2024
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Naturopath Beth O'Hara shares her MCAS journey, while Dr. Michelle Woolhouse discusses genetic variants and treatment options. They dive into the nervous system's role, limbic system balancing, and vagal nerve stimulation for MCAS management.
MCAS symptoms can vary based on dysregulated mast cells and over-released mediators like histamine, prostaglandins, and interleukins.
Stabilizing the nervous system and mast cells is crucial before detoxification for sensitive individuals dealing with MCAS.
Deep dives
Understanding MCAS: Mass Cell Activation Syndrome
Mass Cell Activation Syndrome (MCAS) is a complex immune dysregulation affecting multiple systems and can manifest with or without allergies or anaphylaxis. Symptoms vary based on dysregulated mass cells, receptors, and over-released mediators like histamine, prostaglandins, and interleukins. Patients may experience chronic fatigue, pain, swelling, and various sensitivities. MCAS triggers can include pathogens, stress, and inflammatory conditions like chronic pain and immune disorders.
Stabilizing the Nervous System and Mast Cells
For sensitive individuals, stabilizing the nervous system and mast cells is crucial before detoxification. Removing triggers like mold exposure and tick-borne infections precedes detox efforts. Supporting sleep, cortisol, and addressing root triggers sets the foundation for health. A gradual detox process, focusing on mold, tick-borne infections, gut health, and bone repair, aids in recovery over 2-6 years.
Genetic Analysis and Diagnostic Testing
Genetic analysis in MCAS considers epigenetic influences of triggers on genetic expression. Key genetic markers for histamine breakdown, mast cell stabilization include HDC, DAO, and genes like AOC1. Diagnostic tests for MCAS involve mediator markers like histamine and genetic susceptibility assessments. Routine blood tests for iron, vitamin D, and liver function aid in monitoring health and recovery progress.
Resources and Courses for MCAS Management
For those interested in managing MCAS, resources like the Mast Cell 360 website offer valuable insights and practical tools. Courses on nervous system support, top MCAS supplements, and MC360 Precision Masterclass guide practitioners in navigating MCAS complexities. These courses cover mold detox, supplement protocols, and troubleshooting strategies for challenging cases, aiding in comprehensive treatment approaches.
Naturopath Beth O’Hara shares her experience of 20 years with MCAS, most of those years undiagnosed, which has fuelled her interest to become an expert in MCAS.
Dr. Michelle Woolhouse delves into Beth’s health journey with MCAS and Beth generously shares her clinical pearls on the atypical presentations of MCAS, the relationship of mast cells and the nervous system, genetic variants (SNPs) predisposing someone to MCAS along with treatment options that range from micro dosing supplements, neuroimmunology, limbic system balancing and vagal nerve stimulation.
Find today's transcript and show notes here: https://www.fxmedicine.com.au/podcast/replay-mast-cell-activation-syndrome-dr-michelle-woolhouse-beth-ohara
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***DISCLAIMER: The information provided on fx Medicine is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***
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