The Intern At Work: Internal Medicine 126. Good Bug Gone Bad - Staph Aureus Bacteremia
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Feb 13, 2022 The podcast discusses the clinical manifestations, diagnosis, and management of MSSA and MRSA bacteremia, emphasizing the importance of timely interventions for optimal patient outcomes
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Staph Aureus Colonization And Risk Factors
- Staphylococcus aureus colonizes about one-third of people and ranges from minor skin infections to fatal invasive disease.
- Host defenses and conditions like diabetes, devices, or immunosuppression determine progression to serious infection.
High Mortality And Biofilm Threat
- Untreated Staph aureus bacteremia has very high mortality and commonly originates from skin, lines, bone, lungs, or endocarditis.
- The organism can seed metastatic sites and form biofilms on implants that hinder eradication.
Stabilize First, Then Hunt For Risks
- First ensure patient stability: check GCS, ABCs, and vitals and treat sepsis promptly with fluids, antibiotics, and vasopressors if needed.
- Then gather history for risk factors and symptoms pointing to complications like vertebral osteomyelitis or septic arthritis.