The world, the universe and us

Scientists test engineered microbes to fight disease; Has 1.5 degrees failed?; New theory why we’ve not found aliens

Jul 18, 2025
Madeleine Cuff, an environment reporter from New Scientist, dives into groundbreaking research on genetically engineered microbes that successfully reduce kidney stones by breaking down oxalates. She discusses the looming challenge of extending climate targets, especially as the 1.5C goal seems increasingly unattainable. Lastly, Cuff presents a fascinating theory related to the Fermi paradox, proposing that Earth's unique tectonic activity might be why we haven't encountered alien life. Prepare for a thought-provoking journey through health, climate, and cosmic mysteries!
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INSIGHT

Engineered Gut Bacteria Treat Disease

  • Genetically engineered gut bacteria can successfully colonize the gut and reduce kidney stone-causing oxalates.
  • This breakthrough suggests engineered microbes might treat conditions linked to the microbiome, like Alzheimer's and diabetes.
ADVICE

Using Diet to Control Engineered Microbes

  • To help engineered bacteria establish, feed them a unique carbohydrate they can digest to gain a competitive edge.
  • Stop feeding the carbohydrate to let the engineered bacteria fade away safely after treatment.
INSIGHT

Revising Global Warming Targets

  • Given uncertainties in climate response, aiming for 2°C risks overshoot beyond safe limits.
  • Researchers suggest 1.6-1.7°C as a practical upper limit to keep warming well below 2°C with a decent safety margin.
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