In this episode of ACM ByteCast, Rashmi Mohan is joined by 1974 ACM A.M. Turing Laureate Donald Knuth, author of the hugely popular textbook series, "The Art of Computer Programming." They discuss what led him to discover his love of computing as well as writing about computer programming, his outlook on how people learn technical skills, how his mentorship has helped him write “human oriented” programs, the problems he is still working to solve, and how his dissatisfaction with early digital typesetting led him to develop TeX, as well as his interest in playing and composing music for the pipe organ.