Critical Matters

Capillary Refill Time (CRT)

Nov 19, 2025
Join Dr. Eduardo Kattan, a critical care physician and leading researcher on septic shock, as he discusses the pivotal role of Capillary Refill Time (CRT) in assessing peripheral perfusion. He explains how CRT can guide treatment strategies, especially in early septic shock. With insights from the ANDROMEDA-SHOCK trials, Dr. Kattan highlights the importance of personalized care and the challenges of measuring CRT in diverse populations. His reflections on future research directions and practical tips for implementation make this conversation invaluable for medical professionals.
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INSIGHT

Skin As A Window To Tissue Perfusion

  • The skin serves as a key window into tissue perfusion and can reflect perfusion of visceral organs.
  • Peripheral assessment helps balance continuing resuscitation against avoiding iatrogenic harm.
INSIGHT

Macro-Micro Disconnect In Septic Shock

  • Septic shock involves both macrocirculatory heterogeneity and microcirculatory derangements.
  • Restoring macrodynamics must consider hemodynamic coherence with the microcirculation.
ADVICE

Use Simple Bedside Perfusion Tools

  • Use simple bedside tools like skin temperature gradients, plethysmography-derived perfusion index, laser Doppler, mottling score, and capillary refill time.
  • When using CRT, standardize technique to quantify severity and track changes.
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