PedsCrit

Bronchopulmonary Dysplasia with Dr. Audrey Miller

Aug 25, 2025
Dr. Audrey Miller, an Attending Neonatologist at Nationwide Children's Hospital, shares her expertise on bronchopulmonary dysplasia (BPD). She discusses the complexities of managing BPD in the ICU, emphasizing individualized care strategies. Insights into ventilatory management, patient comfort, and weaning processes are explored, highlighting the importance of collaboration among healthcare teams. Additionally, she addresses the challenges of patient-ventilator asynchrony and the critical support needed for families navigating their child's care journey.
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ANECDOTE

Nationwide's Dedicated BPD ICU

  • Nationwide Children's runs a 24-bed dedicated BPD ICU that admits ~120–130 patients yearly and accepts national referrals.
  • Their unit reports low mortality, low trach rates, good neurodevelopment, and a dedicated multidisciplinary team.
INSIGHT

Heterogeneous Lung Physiology

  • BPD lungs are heterogeneous with few healthy units and many high-resistance, air-trapping regions.
  • These areas have long time constants so exhalation, not inhalation, often limits ventilation.
INSIGHT

Chronic Phase Ventilation Differs From ARDS

  • BPD requires long inspiratory time and very long expiratory time to ventilate high-resistance regions.
  • That physiology leads to low ventilator rates and higher tidal volumes than acute lung strategies.
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