AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Febrile
77: Pièce de (Gram-negative) Resistance, Part 2: CRE
Jul 10, 2023
Drs. Hawra Al-Lawati and Pranita Tamma discuss the management of antimicrobial resistant Gram-negative infections. They explore treatment approaches, testing susceptibility, and advancements in drug resistance. They also discuss alternative treatment options and cases of carbapenem-resistant infections.
33:05
Episode guests
AI Summary
AI Chapters
Episode notes
Podcast summary created with Snipd AI
Quick takeaways
- Choosing appropriate antibiotics based on susceptibility testing and resistance mechanisms is crucial in managing carbapenem resistant gram-negative infections.
- Limited treatment options are available for NDM-producing infections, but potential options include ceftazidime-avibactam and aztreonam combination, ceftriaxone, and cephalosporin-siderophore conjugate (cefiderocol).
Deep dives
Approach to Carbapenem Resistant Entrobacteriaceae (CRE)
This podcast episode discusses the management of carbapenem resistant gram-negative infections, specifically focusing on carbapenem resistant Entrobacteriaceae (CRE) infections. The episode emphasizes the importance of choosing appropriate antibiotics based on susceptibility testing and resistance mechanisms. It highlights the use of drugs such as ceftazidime-avibactam, meropenem-vaborbactam, and ampicillin-sulbactam for CRE infections. It also explores the different carbapenemase genes and their implications for treatment, with specific attention given to KPC, NDM, and OXA-48-like enzymes. The importance of careful dosing and infusion times for optimal drug effectiveness is also discussed.
Get the Snipd
podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any
moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share
& Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered
podcast player
Listen to all your favourite podcasts with AI-powered features
Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode