Mark Jacobstein, Near Horizon GP on AI, Health-Tech & Company Building

Mark Jacobstein is General Partner at Near Horizon, a hands‑on venture studio in Palo Alto that co-founds and builds AI and health-tech startups from day zero. Drawing from over 30 years of entrepreneurial experience founding and scaling companies like Small World Sports (the first online fantasy platform), Digital Chocolate, iSkoot, Guardant Health (led efforts raising over $500 million pre-IPO), Immunai, and Jimini Health, he now combines operational expertise with capital to partner deeply with founders. Mark has been integral to building 11 companies, raising over $1.3 billion, and securing eight exits—including multiple acquisitions and IPOs—positioning him uniquely to guide transformative technology ventures.Topics:

• How to co-found companies as a VC: inside the venture studio model
• From raising $500M+ to backing LLM health startups: fundraising lessons across decades
• Why AI and mental health is one of the biggest (and hardest) opportunities in tech

#AIHealthcare #StartupFundraising #VentureStudios #LLM #MentalHealthTech #CompanyBuilding #VCPlaybook #HealthTechInnovation #FounderAdvice