NEJM This Week NEJM This Week — July 10, 2025
Jul 9, 2025
Explore the latest insights on managing mild asthma and cardiovascular risks. A fascinating discussion unveils new therapies for advanced breast cancer. Learn about juvenile idiopathic arthritis through the lens of a medical editor balancing research with patient care. Delve into a complex case involving neurological symptoms linked to a viral infection and the broader challenges in U.S. healthcare. Finally, discover how immigration policies affect caregiving and the urgent need for a more compassionate healthcare system.
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Mild Asthma Treatment Insight
- Mild asthma patients often underestimate their risk for severe exacerbations despite infrequent symptoms.
- Combining anti-inflammatory budesonide with albuterol as-needed reduces serious asthma attacks better than albuterol alone.
Cardiovascular Risk and Longevity
- Absence of major cardiovascular risk factors at age 50 increases life expectancy by over a decade.
- Midlife improvements in hypertension and smoking status yield most cardiovascular health benefits.
Stroke Treatment Recommendation
- Do not skip intravenous thrombolysis before thrombectomy in large vessel occlusion strokes.
- Use tenecteplase as the preferred thrombolytic in eligible patients admitted within 4.5 hours.
