Short Wave Stopping SSRIs Can Be Hard. Researchers Are Unsure Why
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Sep 2, 2025 In this discussion, Michael Hengartner, a clinical psychology professor in Zurich, dives into the complexities of discontinuing SSRIs, the most commonly prescribed antidepressants. He addresses the challenges patients face, including lasting withdrawal symptoms and the risks of relapse into depression or anxiety. The episode highlights personal stories from individuals grappling with long-term effects and calls for more comprehensive research in this area. Hengartner advocates for increased awareness and better understanding within the psychiatric community.
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Long-Term User's Sudden Withdrawal Experience
- Emily Corwin took Lexapro in her early 20s and stayed on it for about 15 years.
- When she tapered off in 2022 she felt intense existential dread and went back to her original dose which improved things.
Definitions Gap Fuels Confusion
- Michael Hengartner says lack of clear definitions leaves researchers and clinicians uncertain about long-term SSRI problems.
- This void contributes to disagreement on prevalence, prevention, and even naming of withdrawal issues.
Never Abruptly Stop SSRIs
- Do not suddenly stop taking SSRIs; abrupt discontinuation is strongly discouraged.
- Michael Hengartner recommends individualizing taper speed because needs vary widely between patients.