The Herd with Colin Cowherd

Sharp or Square - FINAL NFL WEEK 15 BETS - Bills-Patriots, Packers-Broncos, Vikings-Cowboys, Lions-Rams, Chargers-Chiefs and more

Dec 14, 2025
Get ready for NFL Week 15 as betting experts share their sharpest picks against the spread. They dive into intriguing matchups like the Bills facing the Patriots and the Chiefs battling the Chargers. Key injuries and weather conditions are analyzed to shape their bets. Hear their takes on the Lions-Rams clash, Packers' defensive strategy against the Broncos, and Vikings as underdogs against the Cowboys. With excitement in the air, they unveil their top five betting picks for a thrilling week ahead!
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ADVICE

Get Picks In Early To Capture Value

  • Lock in good numbers early in pick'em contests to maximize value.
  • Exploit line movement and weather factors when they favor your edge.
ADVICE

Bet Situational Advantages In Desperation Games

  • Favor teams in desperate spots when situational factors (weather, injuries) align.
  • Use matchup edges like a weakened offensive line to back the home favorite.
INSIGHT

Bills Will Lean Run To Exploit Patriots Injuries

  • The Bills will prioritize a physical running game to exploit New England's injured front.
  • This matchup feels pivotal for the division and Buffalo will play like it's a must-win.
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