“To fast or not to fast?” When it comes to cholesterol screening, that is the question. Rachel Shustak, MD, and Jordy Martino, MSN, CRNP, an attending cardiologist and a nurse practitioner with the Lipid Heart Clinic at Children's Hospital of Philadelphia, respectively, provide answers to that age-old question plus non-pharmacologic approaches proven to lower cholesterol levels; and more. By taking the ideal screening ages, lifestyle changes and diet recommendations from the American Academy of Pediatrics (AAP) and translating them into real, practical tips for reducing the risk of cardiovascular disease, they help to settle a longstanding debate among primary care physicians. This podcast is for general informational and educational purposes only and is not to be considered as medical advice for any particular patient. Clinicians must rely on their own informed clinical judgment in making recommendations to their patients. ©2023 by Children's Hospital of Philadelphia, all rights reserved.