The Tylenol Murders (with Brad Edwards)

On September 29, 1982, 12-year-old Mary Kellerman took one Extra Strength Tylenol capsule to ease her sore throat and mysteriously died less than four hours later. The same day, three members of the Janus family ingested Tylenol. Brothers Adam and Stanley died hours later. Theresa, Stanley’s wife, experienced chest pain and was rushed to the hospital, where she passed away two days later.

In that span of time, two more victims – Mary Reiner and Mary McFarland – met similar fates. Shortly after, Paula Prince was discovered dead in her apartment

All seven victims were living in the Chicago area; all seven had taken Extra-Strength Tylenol. Authorities determined the capsules had been laced with deadly potassium cyanide; a task force was promptly assembled; and Tylenol’s parent company, Johnson & Johnson, swiftly removed products from shelves amid growing concern around the country. Soon, they introduced tamper-proof packaging that became ubiquitous for medications and other products.

And yet, the crime remains unsolved to this day.

One name loomed large in the field of suspects connected to the unsolved 1982 Chicago Tylenol Murders: James Lewis. Investigators could never prove he did it, but Lewis held a certain fascination anyway. Why? Who was this man – and could he really have committed such an evil crime? CBS Chicago investigative reporter Brad Edwards decided to trace Lewis’s past to answer those questions for the docuseries PainKiller: The Tylenol Murders, on Paramount Plus.

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