Topics covered in the podcast include the causes and distinction of lower GI bleeding from upper GI bleeding, the role of CTA in evaluation, management strategies such as transfusion thresholds and reversal agents, and the importance of timely imaging and resuscitation for unstable patients.
Lower GI bleeding often resolves without intervention, but up to 40% may re-bleed within a year requiring transfusions.
Distinguishing lower from upper GI bleeds is crucial, with factors like history of lower GI bleeding and blood clots per rectum indicating lower GI origin.
Deep dives
Understanding Lower Gastrointestinal Bleeding
Lower gastrointestinal bleeding, which occurs distal to the ligament of trites, is a prevalent condition with over 110,000 admissions and 270,000 ED visits annually in the US. Etiologies include anatomic, vascular, inflammatory, and neoplastic causes. While most cases resolve without intervention, up to 40% may experience re-bleeding within a year, necessitating transfusions in about a quarter of patients.
Differentiating Lower from Upper GI Bleeds
Patients with lower GI bleeding typically present with hematocesia or rectal bleeding. Distinguishing lower from upper GI bleeds is crucial, with factors like a history of lower GI bleeding and blood clots per rectum indicating lower GI origin. Conversely, upper GI bleeding is associated with factors such as melena, age under 50, peptic ulcer history, and elevated BUN to creatinine ratio.
Diagnostic and Treatment Approaches for Lower GI Bleeding
Imaging with CTA is recommended in hemodynamically significant lower GI bleeding cases, offering high sensitivity and specificity when actively bleeding. While resuscitation and consultation with specialists are critical in severe cases, colonoscopy remains the mainstay for diagnosis and treatment, with careful consideration of patient stability, imaging results, and reversal strategies for anticoagulation if needed.