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Gastroenterology Learning Network

Interstitial Lung Disease and Esophageal Disorders: When Specialties Work Together

Jan 2, 2024
Dr. Rita Knotts and Dr. Elizabeth Volkmann discuss the intersection of their specialties in the care of patients with scleroderma, interstitial lung disease, and esophageal conditions. They explore the relationship between reflux disease and lung function, concerns and risks of proton pump inhibitors, the multidisciplinary model for interstitial lung disease and scleroderma, and the collaboration between surgeons and gastroenterologists in managing esophageal disorders.
19:12

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Quick takeaways

  • Patient-reported symptoms of reflux disease in scleroderma patients with interstitial lung disease may be associated with ILD progression.
  • Assessing esophageal motility over time may be more meaningful than a single measurement of esophageal dilation in predicting ILD progression.

Deep dives

Patients with scleroderma-related ILD experienced improvement in FBC with treatments, but some still had progression

The podcast discusses a study that focused on patients with scleroderma-related interstitial lung disease (ILD). The study, called the scleroderma lung study, examined the effectiveness of oral cyclophosphamide and mycophenolate as treatments. While many patients in the study saw improvement in their Forced Vital Capacity (FVC), some continued to experience ILD progression. The researchers aimed to understand the factors that may predict this progression, with a particular focus on the severity of esophageal disease.

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