We are BACK for SEASON FIVE of the pod! In this episode, Dr. Jessica Steier and Dr. Sarah Scheinman discuss Alzheimer's disease and cognitive decline. They cover essential topics including the definition and symptoms of Alzheimer's, the genetic and epigenetic basis of the disease, brain changes associated with Alzheimer's, risk factors such as age, genetics, and lifestyle, modifiable risk factors and prevention strategies, and current treatments and their controversies.

The scientists emphasize that maintaining overall health is crucial for brain health. They recommend a combination of lifestyle choices that promote general well-being, which in turn support cognitive health.

They explore various treatment options, including cholinesterase inhibitors, NMDA receptor antagonists, and monoclonal antibodies targeting amyloid beta. The conversation highlights the ongoing debates about treatment efficacy and the need for further research.

The episode aims to provide valuable insights and alleviate fears surrounding Alzheimer's disease. It concludes with a rapid-fire Q&A segment addressing listeners' questions.

All our sources from this episode are available at: https://www.unbiasedscipod.com/episodes/dont-you-forget-about-me-unraveling-alzheimers

(00:01) Music and Season Five Welcome

(04:30) Introducing Dr. Sarah Scheinman and the Topic of Alzheimer's

(07:49) Understanding Alzheimer's Disease and Its Symptoms

(10:50) The Genetic and Epigenetic Basis of Alzheimer's

(18:23) Risk Factors for Alzheimer's: Age, Genetics, and Lifestyle

(26:02) The Role of Amyloid Plaques and Tau Tangles in Alzheimer's

(30:37) Promoting Early Diagnosis and Intervention for Alzheimer's

(35:21) Breaking Down the Stigma and Building Scientific Literacy

(41:51) Treatments for Alzheimer's Disease

(46:27) Monoclonal Antibodies and Controversy

(53:50) Diagnosing Alzheimer's Disease

(55:32) Final Thoughts: Q&A: Common Questions About Alzheimer's Disease

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PLEASE NOTE: The discussion and information provided in this podcast are for general educational, scientific, and informational purposes only and are not intended as, and should not be treated as, medical or other professional advice for any particular individual or individuals. Every person and medical issue is different, and diagnosis and treatment requires consideration of specific facts often unique to the individual. As such, the information contained in this podcast should not be used as a substitute for consultation with and/or treatment by a doctor or other medical professional. If you are experiencing any medical issue or have any medical concern, you should consult with a doctor or other medical professional.

Further, due to the inherent limitations of a podcast such as this as well as ongoing scientific developments, we do not guarantee the completeness or accuracy of the information or analysis provided in this podcast, although, of course we always endeavor to provide comprehensive information and analysis. In no event may Unbiased Science or any of the participants in this podcast be held liable to the listener or anyone else for any decision allegedly made or action allegedly taken or not taken allegedly in reliance on the discussion or information in this podcast or for any damages allegedly resulting from such reliance. The information provided herein do not represent the views of our employers.

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