The Curbsiders Internal Medicine Podcast #502 Inflammatory Bowel Disease with Dr. Aline Charabaty
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Oct 20, 2025 Dr. Aline Charabaty, a leading gastroenterologist and clinical director at the IBD Center at Johns Hopkins, shares her expertise on inflammatory bowel disease (IBD). She discusses the importance of early diagnosis, differentiating IBD from other GI symptoms, and the latest imaging modalities. Treatment options range from anti-TNFs to dietary strategies for better management. Dr. Charabaty emphasizes preventive health, including vaccinations and screening for nutrient deficiencies, while noting the rising incidence of IBD and the need for a multidisciplinary approach.
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Investigate Any GI Bleeding Promptly
- Take visible GI bleeding seriously and evaluate with colonoscopy, even in young patients.
- Check CBC, iron studies, CMP, celiac serology, CRP and fecal calprotectin to triage further workup.
Fecal Calprotectin Outperforms CRP For Gut Inflammation
- Fecal calprotectin is more gut-specific than CRP and helps detect intestinal inflammation.
- Calprotectin is less sensitive for isolated small-bowel Crohn's and not specific for IBD alone.
Prefer Intestinal Ultrasound Over CT For Monitoring
- Minimize CT use for long-term IBD monitoring to reduce radiation exposure.
- Use intestinal ultrasound where available for bedside assessment and tracking treatment response.