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The Incubator
#186 - đ Journal Club - The latest research in neonatology (Feb 25 2024)
Feb 25, 2024
01:18:56
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This podcast covers the latest research in neonatology including topics like temperature monitoring during therapeutic hypothermia, neonatal outcomes after COVID-19 vaccination in pregnancy, and the increase in maternal syphilis rates. They also discuss studies on therapeutic hypothermia for preterm infants and the impact of innovative monitoring devices in improving neonatal care.
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- MIST therapy in preterm infants on CPAP showed reduced BPD rates and intubation, emphasizing early respiratory interventions.
- Two-year follow-up of the Optimum trial revealed no significant differences in death or neurodevelopmental disability, highlighting long-term respiratory health outcomes.
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Main Trial Outline
The Optimum trial compared minimally invasive surfactant therapy (MIST) to a sham treatment in preterm infants on CPAP. Primary outcome showed no significant difference in death or physiological BPD. Secondary outcomes revealed a decrease in BPD in the survivors, reduced rate of intubation in the MIST group, and no significant difference in the main outcomes.
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