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The Intern At Work: Internal Medicine
229. Ask a Fellow - Hyponatremia Rate of Correction
Mar 14, 2024
Dr. Jeff Kott, a Nephrologist and Critical Care Fellow, discusses hyponatremia correction rates in collaboration with NephMadness. They explore the dangers of rapid sodium level correction, guidelines for correcting hyponatremia in different patient populations, recent studies challenging traditional recommendations, and the debate around correction rates for hyponatremia.
18:46
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Quick takeaways
- Rapid correction of hyponatremia exceeding 12 millimoles per liter within 24 hours poses a higher risk of ODS development.
- Different guidelines emphasize cautious correction rates in high-risk patients to prevent overcorrection and minimize ODS risks.
Deep dives
History and Diagnosis of Osmotic Demyelination Syndrome in Hyponatremia
The discussion delves into the discovery of osmotic demyelination syndrome in the late 1950s, primarily in individuals with alcohol use disorder and malnourishment. Initially, RAS studies linked hyponatremia to ODS in the 1980s, despite early controversies. Notably, rapid correction of hyponatremia exceeding 12 millimoles per liter within 24 hours, especially in severe cases, poses a higher risk of ODS development.
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Discover
highlights
Listen to the best highlights from the podcasts you love and dive into the full episode