

S6 Ep129: It’s a Bundle: Pediatric Sepsis and the New Phoenix Criteria (Part 1)
Jan 15, 2025
Dr. Chris Horvat, a pediatric intensivist and informaticist at UPMC Children's Hospital, joins the discussion on pediatric sepsis and the innovative Phoenix criteria. The conversation dives into the complexities of individualized treatment for pediatric patients, sharing insights from real-life cases. Dr. Horvat emphasizes the critical importance of early recognition of sepsis, particularly in emergency care. They also explore the evolving definitions of sepsis, highlighting the new point-based system that improves diagnostic precision.
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Suspecting Sepsis
- Consider sepsis when a patient has a suspected infection and needs medical assistance.
- This simple approach helps clinicians recognize sepsis early.
Sepsis Definition Evolution
- The old sepsis definition (IPSCC) lacked positive predictive value, leading to overdiagnosis.
- The new Phoenix criteria aim for better precision by focusing on organ dysfunction.
Phoenix Criteria Explained
- The Phoenix criteria use a data-driven, point-based system across four organ systems.
- Two points signify sepsis; two points with cardiovascular dysfunction indicate septic shock.