

VC10X - The Shift From Diagnosis to Prognosis: A New Era in Healthcare - Sam Libby, TCB Capital Advisors
Sep 2, 2025
Sam Libby, a healthcare investment banking veteran and founder of TCB Capital Advisors, is on a mission to improve patient care. He discusses the evolution of AI in healthcare, emphasizing its role in predictive medicine and proactive health management. The conversation explores holistic approaches that integrate mental and physical well-being while addressing patient data democratization. Libby also shares insights on navigating healthcare startup investments, highlighting strategies for early-stage companies and the importance of trust in building investor relationships.
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Career Shift Toward Patient Impact
- Sam Libby left a long banking career because he felt it hadn't tangibly improved patient care.
- He founded TCB Capital Advisors to prioritize patient impact and built a team aligned with that mission.
AI Lowers Barriers And Raises Noise
- AI accessibility and lower costs are accelerating healthcare innovation but increasing market noise.
- Companies with strong clinical data move from concept to market much faster now.
Prognosis Over Late-Stage Treatment
- Longevity and prognostic medicine can reduce downstream neurodegenerative risks.
- Delaying onset of conditions like Alzheimer's can dramatically preserve long-term quality of life.