Dwarkesh Podcast

Holden Karnofsky - Transformative AI & Most Important Century

Jan 3, 2023
Holden Karnofsky, Co-CEO of Open Philanthropy and co-founder of GiveWell, dives into the significance of this century for humanity. He passionately discusses the transformative potential of AI and its ethical implications, urging a balanced approach to innovation. Karnofsky reflects on OpenPhil's $30M grant to OpenAI and the complexities of philanthropy amid uncertainty. He emphasizes the need for thoughtful engagement with emerging technologies and advocates for future-proof ethics to navigate the moral landscape of a rapidly evolving world.
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INSIGHT

Most Important Century Thesis

  • AI systems that can advance science and technology could make this the most important century.
  • This could lead to explosive growth, digital people, and reaching the limits of science and technology.
INSIGHT

AI and the Future

  • Developing advanced AI could lead to a very good or very bad future for humanity.
  • Funding work to shape this transition and increase the odds of a good future helps a huge number of people.
INSIGHT

The Weirdness of Our Time

  • Even ignoring AI, our time is weird due to exploding growth and concentrated technological advancement.
  • We should be nervous, vigilant, and actively consider potential world-transforming events.
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