S2 Ep11: #22 Low Key Pearls for Low Dose Bup With Amelia Goff FNP and Eleasa Sokolski, MD
Sep 14, 2023
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Amelia Goff FNP and Eleasa Sokolski, MD join the hosts to discuss low-dose buprenorphine starts for opioid use disorder, covering physiology, protocols, and troubleshooting challenges faced by patients. They also talk about different formulations of buprenorphine, counseling patients, and considerations for specific patient populations. The episode provides valuable insights on outpatient low dose starts and concludes with key takeaways.
The rapid low-dose buprenorphine initiation protocol in the hospital setting effectively gets patients on buprenorphine by gradually introducing small doses over a four-day period while managing withdrawal symptoms and cravings with full agonist opioids.
The adaptation of the low-dose buprenorphine initiation protocol in the outpatient setting offers patients a more comfortable and timely way to start buprenorphine, but challenges like limited access to full agonist opioids and the need for manual cutting of buprenorphine tablets need to be addressed.
Deep dives
Rapid low-dose buprenorphine initiation in the hospital setting
The podcast episode discusses the implementation and benefits of a rapid low-dose buprenorphine initiation protocol in the hospital setting. The protocol involves gradually introducing small doses of buprenorphine over a four-day period while managing acute opioid withdrawal, cravings, and pain with full agonist opioids. The protocol has been successful in rapidly getting patients on buprenorphine, including pregnant patients and those requiring long-acting extended-release buprenorphine. Challenges include ensuring adequate management of withdrawal symptoms, patient education, and availability of buprenorphine formulations. The protocol has been well-received by patients, providing them with a more comfortable and efficient way to start buprenorphine.
Adapting low-dose buprenorphine initiation in the outpatient setting
The podcast episode also explores the adaptation of the low-dose buprenorphine initiation protocol in the outpatient setting, particularly in harm reduction and bridge clinics. Though challenges exist, such as limited access to full agonist opioids and the need to manually cut buprenorphine tablets or films, the protocol offers patients an opportunity to get on buprenorphine in a more comfortable and timely manner. Health systems should prioritize patient education, access to adjunct medications for withdrawal management, and flexibility in adjusting the protocol based on individual patient needs. Further research and patient perspectives are essential to improve and refine the outpatient implementation of the protocol.
Accelerate your knowledge on low-dose buprenorphine starts for individuals with opioid use disorder. We cover the physiology of how low-dose starts work, different 4-7 day protocols, and how to troubleshoot challenges patients may face. We’re joined by Dr. Eleasa Sokolski, MD (Oregon Health and Sciences University) and Amelia Goff, MSN, FNP (Oregon Health and Sciences University).
Claim free CME for this episode at curbsiders.vcuhealth.org!
By listening to this episode and completing CME, this can be used to count towards the new DEA 8-hr requirement on substance use disorders education.