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The Curbsiders Addiction Medicine Podcast

S2 Ep11: #22 Low Key Pearls for Low Dose Bup With Amelia Goff FNP and Eleasa Sokolski, MD

Sep 14, 2023
Amelia Goff FNP and Eleasa Sokolski, MD join the hosts to discuss low-dose buprenorphine starts for opioid use disorder, covering physiology, protocols, and troubleshooting challenges faced by patients. They also talk about different formulations of buprenorphine, counseling patients, and considerations for specific patient populations. The episode provides valuable insights on outpatient low dose starts and concludes with key takeaways.
51:59

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Quick takeaways

  • The rapid low-dose buprenorphine initiation protocol in the hospital setting effectively gets patients on buprenorphine by gradually introducing small doses over a four-day period while managing withdrawal symptoms and cravings with full agonist opioids.
  • The adaptation of the low-dose buprenorphine initiation protocol in the outpatient setting offers patients a more comfortable and timely way to start buprenorphine, but challenges like limited access to full agonist opioids and the need for manual cutting of buprenorphine tablets need to be addressed.

Deep dives

Rapid low-dose buprenorphine initiation in the hospital setting

The podcast episode discusses the implementation and benefits of a rapid low-dose buprenorphine initiation protocol in the hospital setting. The protocol involves gradually introducing small doses of buprenorphine over a four-day period while managing acute opioid withdrawal, cravings, and pain with full agonist opioids. The protocol has been successful in rapidly getting patients on buprenorphine, including pregnant patients and those requiring long-acting extended-release buprenorphine. Challenges include ensuring adequate management of withdrawal symptoms, patient education, and availability of buprenorphine formulations. The protocol has been well-received by patients, providing them with a more comfortable and efficient way to start buprenorphine.

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