SharkPreneur Episode 1236: Turning Unemployment into a $70 Million Pivot with Rome Madison
What if the year you lost your job and your mother lost her home became the same year you helped build a $70 million breakthrough in medicine?
In this episode of Sharkpreneur, Seth Greene interviews Rome Madison, 3X Best-Selling Author and Keynote Speaker, who shares how growing up with a single mother battling severe mental illness and later homelessness fueled his “no excuses” mindset, and how hand-copying medical textbooks at Barnes & Noble helped him break into precision medicine just as the Human Genome Project was completed. He walks through launching a consulting firm, co-creating the Precision Medicine Podcast that contributed to a $70 million acquisition, and his current work as a confidence coach and host of the global show Genetics for Healthcare, helping high achievers stop second-guessing themselves and expand their impact.
Key Takeaways:
→ The pivotal year when unemployment and a family crisis collided, and why that moment became the catalyst for entering precision medicine.
→ The unconventional way he prepared for a highly technical role by hand-copying medical and molecular biology content from bookstore shelves.
→ A plain-language breakdown of what precision medicine actually is, and how it first transformed cancer care through surgical specimens.
→ Why so many venture-backed precision medicine companies burned through billions, and how that opened the door for his consulting firm.
→ Behind-the-scenes insights into the $70 million acquisition that included the podcast, and the powerful lessons it taught him about ownership, equity, and value creation.
Rome Madison is a dynamic speaker, author, and podcaster who helps people boost self-confidence, face fears, embrace uncertainty, and cut through chaos to achieve bold, ambitious goals. Known for his high-energy delivery and inspiring message, he empowers audiences to take risks and pursue success with fearless determination. A pioneer in the precision medicine industry, Rome draws from extensive sales management and executive leadership experience, sharing powerful lessons from leading massively successful start-ups to navigating the challenges of corporate collapse and restructuring. A futurist with a Specialty in Business Strategy from Harvard Business School Online, he blends forward-thinking insight with real-world expertise. Featured on more than 50 TV and radio programs nationwide, Rome has spoken on global stages, including the Consumer Electronics Show, where he shared his expertise on the Future of Healthcare. His mission is simple yet profound: inspire people to crush their goals, no matter the obstacles.
Connect With Rome :
Website: https://romemadison.com/
Instagram: https://www.instagram.com/romemadisoneverydaysuperstar/
Youtube: https://www.youtube.com/@RomeMadison
Facebook: https://www.facebook.com/TheEverydaySuperstar
LinkedIn: https://www.linkedin.com/in/genomicsellingsolutions/
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