The Revenue Leadership Podcast with Kyle Norton E58: Replacing Your Sales Team with AI Agents (Jason Lemkin, Founder & CEO @ SaaStr)
39 snips
Dec 17, 2025 
Jason Lemkin, founder and CEO of SaaStr and a notable B2B SaaS investor, shares insights on automating sales with AI agents. He discusses the decision to replace underperforming human SDRs with over 20 AI agents, revealing how AI-driven emails generated substantial revenue. Lemkin highlights the importance of a two-vendor bakeoff for selecting tools and advocates for using Salesforce as a central hub for agent activity. He also covers the decline of mid-tier sales roles and the need for tech-savvy leaders to manage AI integrations effectively.
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AI Is A Step Function For GTM
- AI-enabled GTM is a step function: reproduce your best human at scale and get orders-of-magnitude uplift.
- True potential arrives when agents synthesize every org signal into one hyper-personalized outreach.
Use Salesforce As The Agent Hub
- Do centralize agent data in Salesforce and push agent outputs back into the CRM as the shared source of truth.
- Use a GTM nerd to manage agent conflicts before building costly meta-agent orchestration.
Replace Mid-Pack SDRs With Trained AI Agents
- Do replace underperforming, high-cost SDRs with AI agents when turnover and cost make humans unreliable.
- Train agents thoroughly and deploy them with vendor FDE support to avoid chunky failures.