

Episode 50: AI and the non-invasive "brain biopsy" (1H-MRS) with Professor Alex Lin of Harvard Medical School
Feb 1, 2025
Join Professor Alex Lin, a leading expert from Harvard Medical School, as he unveils the groundbreaking technique of non-invasive brain biopsies using hydrogen magnetic resonance spectroscopy (H-MRS). He highlights how this innovative method diagnoses brain tumors linked to genetic mutations without surgery. The conversation dives into the role of AI in interpreting MRS data, enhancing patient outcomes, and tackling the challenges faced in its adoption. Discover how BrainSpec is revolutionizing brain diagnostics and the future of neuroimaging.
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MRS as a Virtual Biopsy
- Magnetic resonance spectroscopy (MRS) measures brain chemistry, not just brain images.
- It acts as a virtual biopsy revealing chemical markers like 2-hydroxyglutarate specific to brain tumors.
Patient Experience of MRS Scan
- MRS scanning feels similar to MRI but sounds quieter and more peaceful.
- No injections or radioactive dyes are needed, making it comfortable for patients.
Spectra Patterns and AI Analysis
- MRS spectra resemble astronomical light spectra showing chemical composition.
- AI can discern patterns to differentiate brain tumors from healthy tissue by chemical differences.