Steve discusses DNA, origin of life, Fermi Paradox, AI, and the Simulation Question. Topics include DNA as molecular information, evolution through natural selection, AI's role in DNA sequencing and phenotypic prediction, timeline of life on Earth, Fermi Paradox explanations, and living in a simulated reality.
DNA carries the information that tells cells how to build themselves, leading to differentiation and specialized cells.
The Fermi Paradox questions the existence of advanced alien civilizations and explores potential explanations for their absence.
Deep dives
DNA and the Transmission of Genetic Information
DNA is a complex molecule found in each cell of our body, carrying the information that tells our cells how to build themselves. Each DNA molecule is the same in every cell, but the signaling mechanisms control how the information in each DNA molecule is expressed, leading to differentiation and the formation of specialized cells.
Evolution and Natural Selection
Evolution works through natural selection, where variations in organisms that are more adapted to their environment are more likely to survive and reproduce. Over time, this process causes species to change and diverge. The transmission of genetic information, variation, and successful adaptations contributes to the development of complex organisms.
The Origin and Development of Life on Earth
Life on Earth originated from favorable conditions and a process of complexification that gradually led to the existence of living organisms like us. The development of life went through different steps such as the emergence of DNA, the transition to multicellular life, and the specialization of different species. The timeline of life on Earth spans billions of years, and the process of complexification is a non-linear one, influenced by various factors.
The Fermi Paradox and Possibilities of Alien Life
The Fermi Paradox questions why, despite the vast number of stars and planets in the universe, we haven't had contact with advanced alien civilizations. Possible explanations include the rare occurrence of complex life, limitations in technological advancement or survival, the existence of advanced civilizations that choose not to contact us, or the potential that we live in a simulated reality. The question of the existence and prevalence of alien life remains open and requires further exploration and knowledge.
Steve discusses DNA and the origin of life on Earth, the Fermi Paradox (is there alien life?), AI and its implications for the Simulation Question: could our universe be a simulation? Are we machines, but don't know it?
CORRECTION: 31:25 The size of our galaxy is not 100 million light years. I should have said ~100 THOUSAND = 100k light years instead!!!
Music used with permission from Blade Runner Blues Livestream improvisation by State Azure.
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Steve Hsu is Professor of Theoretical Physics and of Computational Mathematics, Science, and Engineering at Michigan State University. Previously, he was Senior Vice President for Research and Innovation at MSU and Director of the Institute of Theoretical Science at the University of Oregon. Hsu is a startup founder (SuperFocus, SafeWeb, Genomic Prediction, Othram) and advisor to venture capital and other investment firms. He was educated at Caltech and Berkeley, was a Harvard Junior Fellow, and has held faculty positions at Yale, the University of Oregon, and MSU.
Please send any questions or suggestions to manifold1podcast@gmail.com or Steve on Twitter @hsu_steve.
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