

Ari Brouwer on pivotal mental states & the neurobiology of psychological transformation | Living Mirrors #51
22 snips May 12, 2021
Ari Brouwer, a PhD researcher in psychedelics, discusses the groundbreaking concept of pivotal mental states. He explores how these states can lead to transformative experiences, delving into the roles of psychedelics, spirituality, and even psychosis. The conversation highlights the neurobiological underpinnings of stress, serotonin's influence on behavior, and the cultural significance of these experiences. Brouwer emphasizes the importance of context in shaping psychological transformations, advocating for integrative approaches to mental health treatment.
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Pivotal Mental States (PIMS)
- Pivotal mental states (PIMS) are characterized by increased neuroplasticity and associative learning, offering potential for psychological transformation.
- PIMS can lead to diverse outcomes, ranging from spiritual experiences to psychosis, influenced by context.
Context's Broad Influence
- Context plays a crucial role in shaping the outcome of pivotal mental states, encompassing not only immediate environment but also past experiences and genetics.
- Genetic predispositions, while influential, interact with environmental factors to determine behavioral outcomes.
Serotonin 2A and Transcendence
- The serotonin 2A receptor pathway may be central to experiences of absorption, time dilation, and flow states across various contexts.
- Variations in this pathway could explain the link between spiritual experiences, mystical states, and psychedelic effects.