First reactions | Fred Ramsdell, Nobel Prize in Physiology or Medicine | telephone interview

“I was out walking the dogs and she started yelling, and I thought there was a grizzly bear nearby.” Actually, what Fred Ramsdell’s wife was telling him, while on a hiking trip together, was that he had been awarded the 2025 Nobel Prize in Physiology or Medicine. In this conversation with the Nobel Prize’s Adam Smith, recorded early the following day, Ramsdell recall how the realisation dawned on them. He goes on to speak about the benefits of working in the environment of biotech, the joy of finding talented collaborators, and the importance of celebrating the dedication of those that nurtured hundreds of generations of the all-important scurfy mouse, in which he and Mary Brunkow discovered the FOXP3 gene: “I'm really in awe of the fact that they were able to do that for so long. It's incredible.”

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