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ESC TV Today – Your Cardiovascular News

Season 2 - Episode 12: Immune checkpoint inhibitors and the heart - HDL, HDL therapies and cardiovascular risk

Mar 28, 2024
Experts in cardiology discuss immune checkpoint inhibitors and their impacts on the heart, the importance of HDL and its therapies for cardiovascular health, and the FBI syndrome. Topics include cardiovascular complications of immune checkpoint inhibitors, strategies to elevate HDL levels, and enhancing HDL carriers. The podcast also covers recent key studies in cardiology.
20:49

Podcast summary created with Snipd AI

Quick takeaways

  • Prescription of anti-arrhythmic drugs for atrial fibrillation increases the risk of pacemaker implantation, especially in women.
  • Immune checkpoint inhibitors used in cancer treatment pose acute myocarditis risks, requiring prompt diagnosis and treatment.

Deep dives

Risk of Serious Bradycardia with Anti-Arrhythmic Drugs for Atrial Fibrillation Patients

Prescription of anti-arrhythmic drugs to patients with newly identified atrial fibrillation significantly raises the risk of pacemaker implantation or syncope, with a 3.5-fold increase observed in a Korean study. Notably, women faced a higher risk compared to men, with specific drugs like dronedarone and sotylol showing the largest increase in risk, recommending thorough evaluation before prescribing these drugs.

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