Understanding Subgroups and Special Populations in Clinical Trials

The podcast episode delves into the importance of distinguishing between subgroups and special populations in clinical trials. Subgroups refer to characteristics within a trial population that can be analyzed, such as age, biomarkers, or genetic profiles. On the other hand, special populations like cardiac amyloid doses or genetic cardiomyopathy have pre-specified hypotheses on unique responses. It highlights the significance of terminology precision and the need to comprehend the dissimilarity between these classifications.