Chasing Clarity: Health & Fitness Podcast EP. 123: OZEMPIC & WEGOVY DEEP DIVE: THE SCIENCE OF GLP-1 AGONISTS WITH DR. SCOTT STEVENSON
Aug 15, 2024
Dr. Scott Stevenson, a physician with expertise in metabolism and obesity pharmacology, joins to unravel the complexities of GLP-1 agonists like semaglutide. They discuss the physiological actions of GLP-1, its role in appetite suppression, and how it affects gastric emptying. Scott highlights the positive metabolic effects and weight loss potential, while also addressing concerns about lean mass loss and weight regain after discontinuation. The conversation emphasizes the importance of combining GLP-1s with nutrition coaching for lasting results.
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How GLP-1 Drugs Work
- GLP-1 agonists like semaglutide mimic gut hormone GLP-1 but at prolonged, pharmacological levels.
- They blunt appetite and slow gastric emptying, producing sustained reductions in food intake and improved glycemic control.
Pair Drugs With Behavioral Support
- If your physician prescribes GLP-1 therapy, secure referrals to a nutritionist and exercise coach.
- Build behavioral support because the drug reduces hunger but doesn't teach maintenance skills.
Clients Lost Coverage After Weight Loss
- Brandon recounts clients who lost weight on semaglutide, stopped, then regained everything because insurance stopped coverage.
- One client paid $1,400/month and lost insurance coverage after their BMI fell below the threshold.