Episode 13: NephMadness & Dual-Organ Transplantation: Is 2 Better Than One?
Mar 7, 2024
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Dr. Roslyn Mannon & Dr. Elizabeth Aby discuss dual-organ transplantation, NephMadness 2024, and the differences between liver-kidney and kidney-pancreas transplants. They explore patient selection criteria, transplant challenges, and the effectiveness of these procedures. The podcast also touches on finding joy outside of work and encourages participation in NephMadness brackets.
NephMadness promotes nephrology awareness through competitive education, focusing on complex decision-making in kidney medicine.
Simultaneous Liver Kidney transplants provide immunological advantages and better patient outcomes compared to liver alone transplants, emphasizing the importance of patient selection.
Deep dives
Importance of Neph Madness in Elevating Nephrology
Neph Madness, initiated 12 years ago, aims to elevate the field of nephrology by highlighting areas that need attention. The competition is a fun teaching mechanism where similar topics are pitted against each other, emphasizing the significance of nuanced decision-making in kidney medicine.
Significance of Simultaneous Liver Kidney Transplant
Simultaneous Liver Kidney (SLK) transplant is crucial for patients with liver disease and concomitant kidney complications. Studies show a heightened risk of acute kidney injury and chronic kidney disease post liver transplant. SLK offers immunologic advantages, conferring protection to the kidney allograft and displaying superior patient and graft survival compared to liver alone recipients.
Challenges and Innovations in Transplant Selection
Selecting appropriate dual organ transplant candidates poses challenges, especially in assessing kidney function in liver failure patients. Evolving criteria and allocation schemes necessitate precise patient selection and innovative approaches to optimize outcomes. Safety nets provide priority kidney options for liver transplant patients experiencing kidney-related issues post-operation.
Debate Between Simultaneous Pancreas Kidney and Simultaneous Liver Kidney Transplant
The debate between Simultaneous Pancreas Kidney (SPK) and Simultaneous Liver Kidney (SLK) transplants centers on their respective benefits and challenges. While SPK addresses diabetes-related complications and offers potential metabolic benefits, SLK presents established data on improved patient and graft survival. The discussion reflects differing opinions on the future impact of these dual organ transplant procedures.
It’s Episode 13 of The Nephron Segment and it's time for NephMadness! Join us as we chat with transplant nephrologist Dr. Roslyn Mannon & transplant hepatologist Dr. Elizabeth Aby and discuss all things dual-organ transplantation: liver-kidney, pancreas-kidney, kidney after liver, kidney after pancreas, or even kidney alone?! Listen to the end to hear everyone's picks for NephMadness 2024.
And to be clear, Dr. Mannon supported the Kansas City Chiefs before their Super Bowl 58 win.
Submit your NephMadness brackets here (just like March Madness!) by 3/31. Maximize your changes by submitting 2 brackets per email address.