Ask Doctor Dawn cover image

Ask Doctor Dawn

Inside the Cellular Atlas: From Microbiomes to Holobionts - A Revolutionary View of Life's Complex Interconnections and Disease Patterns

Nov 23, 2024
49:19

Broadcast from KSQD, Santa Cruz on 11-21-2-24:

  • Dr. Dawn introduces the groundbreaking Cellular Atlas project published in Nature journal, explaining how new technology allows unprecedented analysis of cellular interactions and developmental patterns.
  • She explores the concept of holobionts - viewing symbiotic organisms as composite life forms with their microbiomes as co-equal contributors - challenging traditional views of individual organisms.
  • The show delves into examples of holobiont relationships in nature, from bark beetles carrying fungal spores to the complex bacterial communities in human bodies and plant root systems.
  • Dr. Dawn discusses how the holobiont perspective is revolutionizing our understanding of diseases, from cancer microbiomes to colony collapse disorder in bees.
  • She examines practical applications of holobiont research in agriculture, including drought-resistant crops and methods to reduce methane emissions from cattle.
  • The show explores the gut-brain axis and how microbiome interactions influence various diseases including depression, anxiety, and metabolic disorders.
  • She then discusses research identifying that various cancers co-exist in the body with distinct fungal and bacterial microbiomes of their own
  • Dr. Dawn concludes with a discussion of declining iodine levels in the American population, examining dietary changes and potential health implications.

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