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Spatial Web AI Podcast

Exclusive Look at CL1: One-on-One with Cortical Labs’ Chief Scientist

Apr 16, 2025
In a captivating conversation, Brett Kagan, Chief Scientist at Cortical Labs, discusses the revolutionary CL1 system, which merges human neurons with silicon computing for synthetic biological intelligence. He shares insights from the DishBrain experiment, which demonstrated neuron-based gameplay and validated Dr. Friston's Free Energy Principle. The podcast delves into the energy efficiency of biological intelligence compared to traditional AI, the ethical implications of using human neurons in research, and the vast potential applications for drug discovery and personalized medicine.
42:22

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • Cortical Labs has developed the first synthetic biological intelligence system by merging live human neurons with silicon chips, allowing advanced computational capabilities.
  • The successful DishBrain experiment demonstrates biological intelligence's extraordinary energy efficiency and its potential to revolutionize industries like drug discovery and personalized medicine.

Deep dives

Synthetic Biological Intelligence and Cortical Labs

Cortical Labs has pioneered a novel approach to artificial intelligence by developing a synthetic biological intelligence through the fusion of live neurons and silicon chips. The journey began in 2019 with researchers questioning the core elements that contribute to true intelligence found in biological brain cells. By cultivating brain cells in laboratory settings, they aimed to create processors that leverage the advantages of biological systems. A key proof of concept was developed using the classic game Pong, allowing the neurons to learn and improve through real-time interactions.

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