Healio Rheuminations Part 4, The Story of the Antibody: Two Arms and a Stick
The last episode in the series highlighting how the structure of the antibody was discovered, as well as how a chicken butt was critical in understanding B cell biology.
Brought to you by GSK. Consider the long-term impact of disease activity, flares and corticosteroid use on patients with active SLE. Learn more now at treatfortodayandtomorrow.com
- Intro :11
- In this episode :15
- Recap: What we know about the antibody so far 1:12
- Discovering the structure of the antibody 3:34
- What else can we learn about the light chain 7:04
- An understanding of what these proteins were 9:49
Brought to you by GSK. Considering a treatment change for patients with active SLE? Learn about a treatment option for your patients at treatfortodayandtomorrow.com.
- A story about a chicken butt 11:40
- Backtracking to 1898 – where do antibodies come from? 16:49
- An important paper in 1945 argues the lymphocyte is the antibody maker 18:59
- Where is the bursa of Fabricius in humans? 20:46
- A study from Australia 21:48
- The bone marrow is what did it 23:00
- Thanks for listening! 24:48
Disclosures: Brown reports no relevant financial disclosures.
We’d love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum
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Fagraeus A. J Immunol. 1948;58:1-13.
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