Super Human Radio Could Using Your Own Stem Cells for Arthritis Actually Cause More Harm than Good?
32 snips
Jul 8, 2022 AI Snips
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Autologous Stem Cells Can Be Senescent
- Studies show patients with osteoarthritis have high numbers of senescent stem cells in their tissues.
- Elizabeth Yurth warns autologous stem cells can carry that senescence back into the joint.
Senescent Cells Spread Damage Via SASP
- Senescent cells become 'zombie' producers of damaging SASP proteins that induce senescence in neighbors.
- Elizabeth Yurth explains SASPs drive local inflammation and accelerate joint degeneration.
Metabolism Links Obesity To Joint Senescence
- Obesity and altered glucose signalling drive cellular senescence that promotes osteoarthritis beyond mechanical load.
- Elizabeth Yurth connects metabolic inflammation to senescent chondrocytes and joint damage.