Matt Mathison: How to Build, Lose, and Rebuild Better

In this episode, Casey sits down with entrepreneur and investor Matt Mathison to explore how truth, resilience, and purpose define what it really means to thrive. From Wall Street highs to a public collapse, Matt shares how radical transparency, discipline, and faith shaped his comeback and his creation of Allevio, a healthcare platform designed to “empower healing anywhere.”

He unpacks the Thrive Playbook — a practical framework of market tailwinds, operational systems, and maniacal cashflow discipline — showing how great leaders and businesses thrive by aligning people, purpose, and profit. Matt’s story reveals that thriving isn’t about avoiding pain, but transforming it into clarity and action.

For entrepreneurs and high performers, this episode delivers raw lessons on leadership, marriage, and mindset — from rebuilding after loss to creating daily rhythms that keep priorities straight. Through it all, Matt models how truth and love, in business and life, create the foundation for lasting success.

• Learn the three pillars of the Thrive Playbook and how to apply them in your company or personal growth journey.
• Hear the inside story of betting on a billion-dollar Chinese tech company, the short-seller attack that followed, and the courage to tell the truth when everything fell apart.
• See how Allevio scaled from a single idea to a multi-state platform serving patients and providers with purpose and precision.
• Take away relationship and marriage principles that anchor success — from forgiveness and radical communication to shared faith and consistency.

Chapters

00:00 | Welcome & family update

02:07 | Joy in every season: choosing optimism

04:43 | The book that sparked a leadership framework

07:17 | From Wall Street to betting on China

08:23 | Muddy Waters short report & total collapse

13:31 | Redefining “thriving” through loss and truth

19:10 | Removing fear: thriving as forward motion

22:45 | Lessons from failure: transparency and trust

26:46 | Building leaders at every level

29:04 | Hard feedback and preserving relationships

32:10 | The call that sparked Allevio

34:53 | The Thrive Playbook (market, team, cashflow)

37:57 | Mission, vision, and values before scale

41:20 | Cash discipline and operational systems

44:29 | Consistency compounds: the long game

46:53 | Allevio by the numbers

48:36 | Vision: “Empower healing anywhere”

53:26 | Leadership redefined: get better, help others get better

59:05 | Marriage as a partnership through seasons

01:03:00 | Forgive and forget: family wisdom

01:04:26 | Radical communication at home

01:06:52 | Morning runs and connection rituals

01:08:07 | Faith as the cornerstone

01:11:16 | Closing reflections and gratitude

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