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Radiolab

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Nov 24, 2023
Science writer Carl Zimmer, known for his engaging storytelling on evolutionary biology, joins the hosts for a deep dive into the world of giant viruses. They discuss how these colossal microbes challenge conventional definitions of life and blur the lines between living and non-living entities. Zimmer reveals fascinating discoveries like Mimivirus and Pandora virus, leading to questions about evolution potentially going backwards. The conversation is sprinkled with humor and insights, making complex topics accessible and intriguing.
48:09

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Quick takeaways

  • Giant viruses challenge the traditional categorization of viruses as non-living, blurring the line between life and non-life.
  • Giant viruses have undergone a reverse journey from cellular independence to parasitic dependence, challenging the notion of complexity and growth in organisms.

Deep dives

Giant viruses challenge the definition of life

Giant viruses blur the line between life and non-life, challenging the traditional categorization of viruses as non-living entities. These giant viruses were initially discovered as parasites living inside cell hosts. With their complex genetic makeup and ability to build virus factories, they resemble cells more than typical viruses. Scientists are finding a vast variety of giant viruses, ranging from the Mimi virus to the Pandora virus, some with over 1,000 genes. Some theories suggest that giant viruses may have originated as free-living cells, eventually becoming dependent on host cells for survival. The discovery of these giant viruses raises questions about the boundaries and evolution of life.

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