Invest Like the Best with Patrick O'Shaughnessy

D.A. Wallach – Investing in Healthcare - [Invest Like the Best, EP.166]

18 snips
Mar 31, 2020
D.A. Wallach, former lead singer of Chester French and artist-in-residence at Spotify, shares his journey from music to healthcare investing. He discusses how advancements in personalized medicine and genetic therapies are revolutionizing treatment options. Wallach dives into the potential of CRISPR technology and the ethics surrounding gene editing, as well as the complexities of drug pricing in today's healthcare system. He emphasizes the importance of informed choices in healthcare investments and the transformative role of technology in personal health.
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INSIGHT

Medicine's Evolution

  • Medicine is shifting from symptom control (Medicine 1.0) to cures and prevention (Medicine 2.0).
  • Personalized medicine, tailoring treatments to individual biology, is also emerging.
ANECDOTE

A Personal Mutation Story

  • D.A. Wallach's wife has a single mutation in the MLH1 gene, increasing her cancer risk.
  • Gene therapy could potentially address this by introducing functional versions of the defective gene.
INSIGHT

CRISPR vs. Base Editing

  • CRISPR cuts DNA and relies on cell repair mechanisms to introduce edits.
  • Base editing, developed by Beam Therapeutics, offers a more precise approach, changing single DNA letters without cutting.
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