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Discover the evolution of FDA regulations, controversial approval of Vioxx, opioid crisis, FDA's financial ties with pharmaceutical companies, and the agency's role in ensuring drug safety. Uncover the FDA's history, challenges, and failures in protecting the public from harmful products. Dive into the impact of pharmaceutical corporations on medical testing and explore radical solutions to address conflicts of interest within the FDA.
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- FDA's crucial role led by Kelsey in preventing thalidomide tragedy.
- FDA's financial dependence on drug companies impacts impartiality and approval processes.
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Thalidomide Scandal: FDA's Vigilance Tested
Thalidomide, a drug proposed in the late 1950s for sale by Grunenthal Corporation, was prevented from entering the US market by FDA's scientist, Francis Oldham Kelsey. Kelsey's scrutiny and rejection led to averting a catastrophe, as thalidomide caused severe birth defects in other countries post-approval. The incident underscored the FDA's critical role in drug safety evaluation and prompted the 1962 drug amendments, enhancing drug approval scrutiny in the US.
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