Psilocybin and MDMA | ice baths | antidepressants for pain

The Therapeutic Goods Administration recently approved the psychedelic compound psilocybin for treatment-resistant depression; and MDMA–or ecstasy–for treatment-resistant post-traumatic stress disorder. A group of researchers think this is premature.

More people are tackling the bracing discomfort of ice bath sessions—for the touted health benefits ... but there are some serious risks, so pay attention to the instructions before hopping in.

Chronic, non-cancer-related pain is hard to treat and so alternate medications—like antidepressants—are used because of their action on the brain. A group of researchers has compiled the available evidence on their efficacy.